Positive Minds Strong Joints for Knee Osteoarthritis
United States39 participantsStarted 2025-02-17
Plain-language summary
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
Who can participate
Age range
50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
INCLUSION CRITERIA:
* Age≥50
* BMI ≤ 40 kg/m2
* Self-identify as Black (including African American)
* Knee pain ≥4/10 on a 11 numeric scale over the past week
* Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7)
* Can speak and understand English at a sufficient level to understand the study procedures and informed consent
* Available for study duration
* Able to attend remote sessions
EXCLUSION CRITERIA
* Knee, hip or ankle replacement
* Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months
* Knee surgery within past 6 months
* Currently receiving or received within 3-months any PT for knee OA
* Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments)
* Planning to initiate physical therapy for joint or low back pain in the next 3months
* Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month.
* Systemic inflammatory arthritis (e.g., rheumatoid arthritis)
* Neurologic conditions (e.g., stroke, Parkinson's disease, etc.)
* Contraindications to starting an exercise program.
* Suspected substance abuse
* Lack capacity to consent
* Pregnancy (self-report)
* Participation in another clinical trial for any joint or muscle pain
* Planning for a major surgery in the next 6 months
* Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, ps…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Recruitment Rate
Timeframe: Throughout the recruitment process
2
Retention
Timeframe: From the start of the study to end of the 10 week intervention