Angina

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Angina trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 34 trials

RecruitingNot Applicable

NCT06896903

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants there…

United States50 participantsStarted 2025-05-21

Treatment: Coronary reactivity testing with and without nitrates

RecruitingNot Applicable

NCT04347200

REGistry of Long-term AnTithrombotic TherApy-1

To assess the rates of ischemic and hemorrhagic complications of long-term antithrombotic therapy in patients with chronic coronary syndromes

Russia2,000 participantsStarted 2015-01-15

Treatment: Antiplatelet Drug

RecruitingNot Applicable

NCT06070662

Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study

* 40% of patients presenting with stable chest pain (angina) have no significant blockage of the main heart arteries. Identifying why these patients have sympto…

United Kingdom20 participantsStarted 2023-11-01

Treatment: Coronary microvascular disease testing during coronary angiography, Cardiac magnetic resonance scan including exercise

RecruitingNot Applicable

NCT03581318

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Background: Magnetic resonance imaging (MRI) is an important non-invasive tool to study and diagnose cardiovascular disease. MRI scanners use strong magnetic f…

United States5,000 participantsStarted 2018-07-12

RecruitingNot Applicable

NCT05102019

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

To demonstrate the safety and effectiveness of the Shockwave Reducer for treatment of patients with refractory angina pectoris treated with maximally tolerated…

United States380 participantsStarted 2022-01-04

Treatment: Arm 1: treatment with Shockwave Reducer, Arm 2 (control): Implantation procedure with no device implanted

RecruitingNot Applicable

NCT06313645

Vascular Senescence and Atherosclerotic Plaque Vulnerability

Chronological aging significantly contributes to structural and functional alterations in the vasculature, making it a major risk factor for atherosclerotic dis…

Italy300 participantsStarted 2023-07-01

Treatment: Several biomarkers

All recent trials (100 shown)

Not Yet RecruitingNot Applicable

NCT07558018

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA

The primary objective of this project is to validate a multi-modal systemic microvascular phenotyping platform-combining Laser Speckle Contrast Imaging (LSCI) a…

Location not specified60 participantsStarted 2026-08

Treatment: Investigation of Systemic Endothelial Microvascular Function

TerminatedPhase 2

NCT04614467

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

This clinical trial will explore the efficacy and safety of GCSF-mobilized autologous CD34+ cells for the treatment of CMD in adults currently experiencing angi…

United States34 participantsStarted 2020-10-29

Treatment: CLBS16, Placebo

Angina

Trial phase breakdown

Trial status

Actively recruiting — 34 trials

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

REGistry of Long-term AnTithrombotic TherApy-1

Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Vascular Senescence and Atherosclerotic Plaque Vulnerability

All recent trials (100 shown)

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Trial phase breakdown

Trial status

Actively recruiting — 34 trials

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

REGistry of Long-term AnTithrombotic TherApy-1

Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Vascular Senescence and Atherosclerotic Plaque Vulnerability

All recent trials (100 shown)

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Comprehensive Invasive Physiological Evaluation of Obstructive Coronary Artery Disease

The International Survey of Acute Coronary Syndromes-ARCHIVES

Microvascular Dysfunction in Patients With Long-Covid Syndrome and Angina

Echocardiography: Value and Accuracy at REst and STress

A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients

ANti-Oxidant in Variant Angina (ANOVA) Trial

Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)

Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Pr…

Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurement…

Hybrid Exercise Program for Heart Disease: Effect on Health and Quality of Life

Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individ…

The Role of Inflammation in Myocardial Infarction

Wave Crossover ECP Study for Simplified Therapy

Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology

Angiography-Derived Physiological Indices for Outcome Prediction in Patients Undergoing OCT-Guided PCI

REDUCER-I: An Observational Study of the Neovasc Reducer™ System

Prospective Lifespan Cohort of Myocardial Infarction

Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina