Alzheimer Dementia (AD)

Clinical trial pipeline · Data from ClinicalTrials.gov

See which Alzheimer Dementia (AD) trials you may qualify for

100

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

RecruitingPhase 1

NCT07169630

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

Background: About 5 million adults in the United States have age-related brain disorders. These include Alzheimer disease (AD), mild cognitive impairment (MCI)…

United States90 participantsStarted 2026-05-13

Treatment: 18F-PF974, 18F-florbetaben

RecruitingNot Applicable

NCT07425769

Adapting RDAD for DS

The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older ad…

United States40 participantsStarted 2026-03-31

Treatment: Remote Exercise Sessions, Caregiver Education Sessions

RecruitingNot Applicable

NCT05151562

Music Therapy for Patients With Alzheimer's Disease

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood…

United States60 participantsStarted 2022-07-18

Treatment: Virtual Music Therapy

RecruitingNot Applicable

NCT07570719

Community-based Screening for Alzheimer's Disease

The goal of this prospective, multicenter, observational cohort study is to evaluate the screening performance of blood-based biomarkers for Alzheimer's disease…

China3,000 participantsStarted 2026-05-01

Treatment: No study-specific intervention

RecruitingNot Applicable

NCT05877196

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

The goal of this clinical trial is to test 6 months of aerobic exercise in older adults who are 65 years or older and have mild cognitive impairment (MCI) or pr…

United States216 participantsStarted 2023-06-22

Treatment: Moderate Intensity Continuous Training (MICT), Chair-based Stretch

RecruitingNot Applicable

NCT05592678

δ in Dementia Clinical Trials

The goal of this clinical trial is to demonstrate potential improvements in clinical trial methods relating to dementia and cognitive decline. The main question…

United States200 participantsStarted 2024-08-05

Treatment: Donepezil

All recent trials (100 shown)

Active — Not RecruitingNot Applicable

NCT04122001

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Alzheimer's disease (AD) is the leading neurodegenerative disease of aging characterized by multiple cognitive impairments. Given the recent failures of disease…

United States94 participantsStarted 2020-08-17

Treatment: Active, in-person HD-tDCS or active remote tDCS, Sham

Active — Not RecruitingPhase 1

NCT05464368

R21 Roche: 3-Way Tau Tracers in AD

This is an open label study to compare three new generation TAU radioligands, 18F-RO948 (formerly known as 18F-6958948), 18F-MK6240, and \[18F\]GTP1for imaging…

United States38 participantsStarted 2023-02-01

Treatment: [18F]RO-948, 18F-MK6240

Alzheimer Dementia (AD)

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

Adapting RDAD for DS

Music Therapy for Patients With Alzheimer's Disease

Community-based Screening for Alzheimer's Disease

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

δ in Dementia Clinical Trials

All recent trials (100 shown)

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

R21 Roche: 3-Way Tau Tracers in AD

Trial phase breakdown

Trial status

Actively recruiting — 40 trials

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

Adapting RDAD for DS

Music Therapy for Patients With Alzheimer's Disease

Community-based Screening for Alzheimer's Disease

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

δ in Dementia Clinical Trials

All recent trials (100 shown)

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

R21 Roche: 3-Way Tau Tracers in AD

LiO-AD: Lithium Orotate in Alzheimers Disease Feasibility, Biomarker Engagement, and Clinical Response

Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases

Phase 1 Study to Evaluate the Safety and Tolerability of 8M2D in Healthy People and Alzheimer's Patients

High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults

Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD

Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)

Study of Neural Stem Cell-Derived Exosomes in Moderate-to-Severe Early-Onset Alzheimer's Disease

A Study Testing Whether Low-Dose Radiation Could Help the Immune System and Possibly Improve Early-Onset Alzheimer's Dis…

Telemedicine Self-examination of Speech and Memory for Rapid Detection of Cognitive Impairments Using Machine Learning M…

Learning Skills Together Family Caregiver Complex Intervention

Decision Making Tool for Firearm Storage

A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease

Amyloid Monoclonal Antibody Treatment in PD Patients With Coexistent AD Pathology

Choline Effects - Pre-symptomatic AD

Genetics of Mendelian Forms of Young Onset Alzheimer Disease

Feasibility of Improving Glycemia With Heat Therapy to Prevent AD

Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD)

Improving Dementia Care in Primary Practice