Falls: A Marker of Preclinical AD (NCT04949529) | Clinical Trial Compass
CompletedNot Applicable
Falls: A Marker of Preclinical AD
United States355 participantsStarted 2019-03-07
Plain-language summary
This longitudinal cohort study investigates cognitively normal participants with and without preclinical Alzheimer disease (AD) in order to examine: (1) the relationship between falls and functional mobility in preclinical stages of AD; and (2) a hypothesized model of central and peripheral mechanism(s) underlying falls and functional mobility in preclinical stages of AD.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. 65 years of age or older
. cognitively normal (Clinical Dementia Rating \[CDR\] score of 0)
. have biomarkers (CSF), and/or neuroimaging (positron emission tomography \[PET\] and/or magnetic resonance imaging \[MRI\]) within 2 years of enrolling in this study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study looked at falls as a possible early marker of Alzheimer's disease — does my history of falls, or my loved one's, suggest it would be worth having a conversation about Alzheimer's risk screening?
2Since this trial is already completed, have the results been published, and if so, what did they find about the connection between fall severity and early Alzheimer's disease?
3Could the way my falls are happening — how hard they are, how often — actually be telling us something about what's going on in my brain, and is that something my care team is currently evaluating?
4If falls can signal preclinical Alzheimer's, are there other assessments or tests you'd recommend I do now, rather than waiting to see if cognitive symptoms develop?
5Would you say my current fall prevention plan takes into account the possibility of an underlying neurological cause, or should we look more closely at that angle?'?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.