AIDS-Related Dementia Complex

Clinical trial pipeline · Data from ClinicalTrials.gov

See which AIDS-Related Dementia Complex trials you may qualify for

Total trials

Actively recruiting

Phase 3 trials

Completed

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

RecruitingPhase 1/2

NCT05586581

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

The purpose of this study is to longitudinally characterize and evaluate changes in synaptic density in the brain using novel positron-emission tomography (PET)…

United States70 participantsStarted 2023-05-17

Treatment: SV2A PET, TSPO PET

RecruitingNot Applicable

NCT06885918

ALS Research Collaborative

The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings…

United States2,000 participantsStarted 2014-09-12

RecruitingNot Applicable

NCT04330287

HIV-HEART Aging Study

The HIV/HEART Aging study (HIVH) is an ongoing, prospective, multicentre trial that was conducted to assess the incidence, the prevalence and the clinical cours…

Germany2,000 participantsStarted 2020-05-11

All recent trials (44 shown)

CompletedNot Applicable

NCT04428112

Rural Dementia Caregiver Project

Rural caregivers face challenges of geographic isolation and lower health care access and quality. Many rural dementia caregivers experience serious health cons…

United States418 participantsStarted 2020-06-05

Treatment: Building Better Caregivers Workshop, Attention Control

CompletedPhase 2

NCT03384784

Effect of Galantamine on Inflammation and Cognition

This study tests whether galantamine (GAL) reduces HIV-related inflammation and cognitive deficits. In this double-blind placebo-controlled crossover study, HIV…

United States63 participantsStarted 2017-10-30

Treatment: Galantamine, Placebo

AIDS-Related Dementia Complex

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

ALS Research Collaborative

HIV-HEART Aging Study

All recent trials (44 shown)

Rural Dementia Caregiver Project

Effect of Galantamine on Inflammation and Cognition

Trial phase breakdown

Trial status

Actively recruiting — 3 trials

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy

ALS Research Collaborative

HIV-HEART Aging Study

All recent trials (44 shown)

Rural Dementia Caregiver Project

Effect of Galantamine on Inflammation and Cognition

Teleneuropsychological Intervention in Asymptomatic HIV Seropositive Patients: N&C NeuroChange

Exploring Racial Disparities in Sleep Health and Neurocognitive Function

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies

Evaluation of the Role of OCT in the Detection of HIV-associated Neurocognitive Disorder

Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Comple…

A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Comp…

Safety and Effectiveness of the Selegiline "Patch" for Decreased Mental Function in HIV Patients

An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Co…

Individualized Cognitive Training in HIV

Maraviroc and NeuroAIDS Pathogenesis

Intranasal Insulin for the Treatment of HAND

Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

Effect of Cenicriviroc on HIV Neurocognitive Impairment

Neurocognitive Impairment and Psychiatric Comorbidities in HIV-1

HIV&HEART Aging Study (12,5 Year Follow up)