TU-100 for Accelerating GI Recovery After Major Abdominopelvic Surgery (RC & CAWR)

Inclusion Criteria: * Male or female participants aged 18 years or older * American Society of Anesthesiologists (ASA) Physical Status Classification I-III * Scheduled to undergo elective open or minimally invasive Radical Cystectomy (RC) with continent or incontinent urinary diversion requiring bowel resection, or open or complex minimally invasive surgery for Complex Abdominal Wall Reconstruction (CAWR) with anticipated myofascial advancement flap and mesh placement for moderate or giant hernia defects * Body mass index (BMI) ≤40 kg/m² * Women of childbearing potential and men with partners of childbearing potential must agree to use highly effective contraception * Willing and able to comply with study procedures and able to voluntarily provide informed consent Exclusion Criteria: * Not scheduled for a Radical Cystectomy (RC) or Complex Abdominal Wall Reconstruction (CAWR) procedure meeting the inclusion criteria * Known gastric or bowel obstruction * Have had or have planned gastrectomy, gastric bypass, colostomy, or ileostomy * Significant gastrointestinal motility disorders * Pregnancy or breastfeeding * Clinically significant hepatic, renal, cardiovascular, or other uncontrolled medical conditions * Immunocompromised state or recent immunosuppressive therapy