CompletedNot Applicable

Effect of Pyramidal Aerobic Training on Ventilatory Function in Cigarette Smokers

Egypt40 participantsStarted 2025-09-06

Plain-language summary

Statement of the problem: Does the pyramidal aerobic training affect ventilatory function parameters in smokers? Null hypothesis: Pyramidal aerobic training has no significant effect on ventilatory function parameters (such as Forced Vital Capacity \[FVC\], Forced Expiratory Volume in one second \[FEV₁\], and Peak Expiratory Flow Rate \[PEFR\]) in adult smokers.

Who can participate

Age range

18 Years – 28 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Cigarette smoker males aged from 18 to 28 years. * Smoking index = 50. * Sedentary lifestyle. * BMI between 18.5 and 29.9 kg/m². * Cigarette smokers demonstrate mild to moderate impairment in ventilatory function confirmed by baseline spirometry. * SASEQ (Smoking Abstinence Self-Efficacy Questionnaire) moderate self-efficacy, score from 9 to 16. * Cigarette smokers are able and willing to participate in aerobic training sessions Exclusion Criteria: * Patients diagnosed with chronic respiratory diseases such as asthma. * Patients with cardiovascular diseases or other systemic illnesses that contraindicate exercise. * Patients who experienced recent respiratory infections within the last 4 weeks. * Patients currently engaged in regular structured aerobic or respiratory training programs.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Forced Expiratory Volume in 1 Second (FEV1)

Timeframe: Baseline and after 8 weeks of intervention

Forced Vital Capacity (FVC)

Timeframe: Baseline and after 8 weeks of intervention

FEV1/FVC Ratio

Timeframe: Baseline and after 8 weeks of intervention

Peak Expiratory Flow Rate (PEFR)

Timeframe: Baseline and after 8 weeks of intervention

Trial details

NCT IDNCT07765485

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-10

View on ClinicalTrials.gov More Cigarette Smoking trials

Plain-language summary

Who can participate

Age range

18 Years – 28 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Forced Expiratory Volume in 1 Second (FEV1)

Timeframe: Baseline and after 8 weeks of intervention

Forced Vital Capacity (FVC)

Timeframe: Baseline and after 8 weeks of intervention

FEV1/FVC Ratio

Timeframe: Baseline and after 8 weeks of intervention

Peak Expiratory Flow Rate (PEFR)

Timeframe: Baseline and after 8 weeks of intervention