Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Foot Calluses and Corns (NCT07765225) | Clinical Trial Compass
CompletedNot Applicable
Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Foot Calluses and Corns
Poland124 participantsStarted 2020-02-01
Plain-language summary
This prospective, non-randomized, controlled study evaluated the efficacy of a topical cosmetic keratolytic preparation (serum and cream containing urea, salicylic acid, and collagen) in reducing the thickness and associated pain of hyperkeratotic foot lesions (calluses and corns). High-frequency ultrasonography (18 MHz) was used for precise, quantitative measurement of lesion thickness before and after a two-month intervention. Participants were allocated to four parallel groups (treated calluses, untreated callus controls, treated corns, and untreated corn controls).
Who can participate
Age range
35 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult women aged 35-65 years.
* Presence of a single non-infectious hyperkeratotic foot lesion classified as either a callus or a corn.
* Written informed consent provided prior to study initiation.
Exclusion Criteria:
* Known allergy or hypersensitivity to salicylic acid, salicylates, or other formulation ingredients.
* Active dermatological conditions, skin diseases, or epidermal fissures on the lower extremities.
* Diabetes mellitus.
* Active cardiovascular disorders or local inflammatory conditions.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Hyperkeratotic Lesion Thickness
Timeframe: Baseline and 2 months
Trial details
NCT IDNCT07765225
SponsorWroclaw University of Health and Sport Sciences