Sarcopenia in Acute Ischemic Stroke (NCT07764172) | Clinical Trial Compass
RecruitingNot Applicable
Sarcopenia in Acute Ischemic Stroke
Russia400 participantsStarted 2026-08
Plain-language summary
The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental verification and functional-cognitive assessments, and to evaluate its impact on functional outcome at three months. The main research question is:
Is the presence of sarcopenia at admission associated with less favorable stroke outcomes, including higher rates of complications and mortality?
Participants receiving standard medical care for acute ischemic stroke will undergo extended functional assessment for sarcopenia, and a subset will additionally undergo cognitive evaluation.
Who can participate
Age range
50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 50 years and older
* Acute ischemic stroke confirmed by CT or MRI
* Admission within the first 72 hours
* Written informed consent and availability of a contact telephone number for follow-up
Exclusion Criteria:
* TIA without a visible lesion on neuroimaging; bilateral hemiparesis
* Amputations or severe contractures that preclude anthropometric assessment
* Active cancer at stage IV or life expectancy of less than 3 months
* Neuromuscular diseases; chronic use of systemic glucocorticoids for more than 3 months
* Pregnancy; refusal to participate
Discontinuation criteria (drop-out)
* Discharge or death within the first 7 days
* Withdrawal of consent
* Transfer to another facility resulting in loss of contact
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline in Barthel Index for Activities of Daily Living at 14 days
Timeframe: Baseline and 14 days
2
Change from Baseline in Modified Rankin scale at 90 days
Timeframe: Baseline and 90 days
Trial details
NCT IDNCT07764172
SponsorUniversity Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)