Autologous Nanofat Injection for Treatment of Stable Vitiligo (NCT07763262) | Clinical Trial Compass
CompletedNot Applicable
Autologous Nanofat Injection for Treatment of Stable Vitiligo
Egypt20 participantsStarted 2024-04-01
Plain-language summary
This randomized, split-site, within-participant controlled clinical study evaluated the efficacy and safety of a single session of autologous nanofat injection as an adjunct to narrowband ultraviolet B (NB-UVB) phototherapy in 20 adult patients with stable vitiligo. In each participant, one vitiligo site received autologous nanofat injection followed by NB-UVB phototherapy three times weekly for 3 months, while a comparable site received NB-UVB phototherapy alone. Treatment response was assessed by standardized photography performed by a blinded dermatologist, with evaluation of the onset and percentage of repigmentation, patient satisfaction, and treatment-related adverse effects.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 years or older.
* Male or female patients.
* Patients with clinically diagnosed stable vitiligo.
* Presence of comparable vitiligo sites suitable for the split-site study design.
* Ability to undergo autologous nanofat harvesting and injection.
* Ability and willingness to undergo NB-UVB phototherapy three times weekly for 3 months.
* Ability to comply with study follow-up and assessment procedures.
* Provision of written informed consent.
Exclusion Criteria:
* Active or progressive vitiligo.
* Active infection or inflammation at the treatment sites.
* Significant uncontrolled systemic disease that could interfere with treatment or assessment.
* Contraindication to NB-UVB phototherapy.
* Contraindication to the nanofat harvesting or injection procedure.
* Pregnancy or breastfeeding, if this was an exclusion criterion in your protocol.
* Previous treatment of the selected study sites that could interfere with assessment.
* Inability to comply with the study protocol or follow-up.
* Any condition considered by the investigator to interfere with the safety or assessment of the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.