The Latino Youth and Family Empowerment Study - III (LYFE-III): Bringing to Scale a Culturally-Ad… (NCT07761052) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Latino Youth and Family Empowerment Study - III (LYFE-III): Bringing to Scale a Culturally-Adapted and Evidence-Based Intervention for Latino Families
200 participantsStarted 2026-09
Plain-language summary
The objective of this study is to harness digital technology to bring to scale a culturally adapted and evidence-based parenting intervention for Latinos (Nuestras Familias: Andando Entre Culturas). The Latino Youth and Family Empowerment - III study (LYFE-III) proposed here will adapt, scale, and evaluate the efficacy of an online version of Nuestras Familias with Latino parents and youth in a randomized controlled trial (RCT). The specific aims are as follows:
Aim 1. To adapt the Nuestras Familias intervention to an online format that can be widely accessed by underserved Latino families. This process includes intervention refinement, enhancing efficiency, and manualization of intervention content
Aim 2. Conduct a small randomized controlled pilot trial to (a) test the online program's promise while evaluating changes in target mechanisms of action (i.e., parenting practices) and their subsequent effects on youth mental health outcomes; and (b) to evaluate the feasibility, appropriateness, and acceptability of the online version of the Nuestras Familias intervention.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* The family identifies as Latino or Hispanic.
* The family includes a child in the sixth or seventh grade.
* The child is newly enrolled in or has recently begun receiving services through Breakthrough Central Texas.
* At least one parent or primary caregiver speaks Spanish.
* A parent or primary caregiver and the participating child are willing to complete study assessments.
* The parent or primary caregiver agrees that the family may be randomly assigned to either the LYFE-III intervention group or the services-as-usual group.
* The parent or primary caregiver is willing to complete the online parenting program if assigned to the LYFE-III intervention group.
* The parent or legal guardian is willing to provide informed consent, and the child is willing to provide assent.
Exclusion Criteria
* The parent or primary caregiver is currently participating in another parenting education or parent-training program.
* A participating parent or child has an active, severe mental health condition, such as schizophrenia or another psychotic disorder, that would make participation in a preventive parenting program inappropriate.
* A participating parent or child has mental health or substance-use needs that, after review by a study psychologist, require a higher level of care than the LYFE-III prevention program provides.
* The parent or child is unable or unwilling to complete the study procedures or participate in the assigned study condition.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Parent-Reported and Youth-Reported General Parenting Scale Mean Score From Baseline to Immediately Post-Intervention
Timeframe: Baseline and immediately after completion of the approximately 3-week intervention
2
Mean Acceptability of Intervention Measure Score Immediately Post-Intervention
Timeframe: Immediately after completion of the approximately 3-week intervention
3
Mean Intervention Appropriateness Measure Score Immediately Post-Intervention
Timeframe: Immediately after completion of the approximately 3-week intervention
4
Mean Feasibility of Intervention Measure Score Immediately Post-Intervention
Timeframe: Immediately after completion of the approximately 3-week intervention