Fresh Gas Flow Rate and Perioperative Lung Aeration Assessed by Lung Ultrasound in Septoplasty (NCT07758517) | Clinical Trial Compass
CompletedNot Applicable
Fresh Gas Flow Rate and Perioperative Lung Aeration Assessed by Lung Ultrasound in Septoplasty
Turkey (Türkiye)2 participantsStarted 2024-01-10
Plain-language summary
This prospective, single-center observational cohort study evaluated the association between fresh gas flow rate during inhalational anesthesia and perioperative changes in lung aeration in adults undergoing elective surgery for nasal septal deviation.
Participants were classified into two cohorts according to the fresh gas flow rate used during routine anesthesia care: 1 L/min or 3 L/min. The flow rate was selected independently by the attending anesthesiologist as part of routine clinical practice and was not assigned by the research protocol.
Lung aeration was assessed using the modified lung ultrasound score before anesthesia, after tracheal intubation, before extubation, 15 minutes after admission to the post-anesthesia care unit, and before discharge from the post-anesthesia care unit. Perioperative oxygenation, hemodynamic variables, respiratory mechanics, and early postoperative recovery findings were also recorded.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 to 65 years
* Scheduled to undergo elective septoplasty for nasal septal deviation under general anesthesia
* American Society of Anesthesiologists physical status I or II
* Body mass index of 35 kg/m² or less
* Provided written informed consent to participate
Exclusion Criteria:
* Acute respiratory tract infection within the preceding 15 days
* Chronic pulmonary disease
* Malignancy
* Significant hepatic, renal, or cardiac disease
* Limited ability to cooperate with the study assessments
* Cerebrovascular or neuromuscular disease
* Previous thoracic surgery
* Chest wall deformity
* Emergency surgery
* History of clinically relevant allergy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Perioperative Change in Modified Lung Ultrasound Score
Timeframe: Preoperative baseline; after tracheal intubation; before extubation; 15 minutes after PACU admission; and approximately 30 minutes after PACU admission or before PACU discharge
Trial details
NCT IDNCT07758517
SponsorFatih Sultan Mehmet Training and Research Hospital