Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia (NCT07757984) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia
Taiwan150 participantsStarted 2026-09-01
Plain-language summary
The goal of this observational study is to learn about the impact of sarcopenia (muscle loss) on the efficacy of regional nerve blocks and postoperative recovery in patients undergoing upper extremity surgery. The main questions it aims to answer are:
1. Does sarcopenia affect the onset time and success rate of peripheral nerve blocks?
2. How does sarcopenia influence postoperative pain control and opioid consumption compared to patients receiving pure general anesthesia?
Participants will undergo a preoperative muscle assessment, which includes a chair stand test and a brief ultrasound of the thigh muscle. Researchers will then observe and record their nerve block onset time (if applicable), postoperative pain scores, and recovery metrics during their hospital stay up to postoperative day 2.
Who can participate
Age range
50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age\>=50 years old
* ASA I-III
* Receiving upper limb surgery under general anesthesia
Exclusion Criteria:
* Severe cognitive impairment or inability to cooperate with pain and motor assessment
* Pre-existing neuropathy of the musculocutaneous, median, radial or ulnar nerve
* (for nerve block group) Contraindications to regional nerve blockade
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
time to first rescue analgesia
Timeframe: From the completion of surgery up to Postoperative Day 2