The clinical trial is investigating the oral administration of probiotic Streptococcus salivarius K12 in the form of lozenges in healthy adults. The main outcome measures are: * Potential for Streptococcus salivarius K12 to colonise the oral cavity * Effect on other bacteria and Candida albicans in the oral cavity * Possible anti-inflammatory effect Participants will: * Take one lozenge containing Streptococcus salivarius K12 daily for 4 weeks * Attend 3 dental check-ups (before starting the probiotic treatment, and after 4 and 8 weeks) * Collect their own saliva samples in accordance with a sampling schedule
Age range
18 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Impact of Streptococcus salivarius K12 on oral colonization
Timeframe: Baseline, intervention, and washout samples are collected according to a sampling schedule for 8 weeks.
Impact of Streptococcus salivarius K12 on oral colonization
Timeframe: Three dental plaque samples are analysed: baseline, intervention (after 4 weeks), and washout (after 8 weeks)
Impact of Streptococcus salivarius K12 on oral colonization
Timeframe: Three saliva samples are analysed: baseline, intervention (after 4 weeks), and washout (after 8 weeks)