This prospective multi-cohort observational study evaluates the association between peripheral blood lipidomic and ceramide profiles and atrial fibrillation. The study hypothesis is that peripheral blood lipidomic features and ceramide-related profiles are associated with the presence of atrial fibrillation. Participants with atrial fibrillation and control participants with other cardiovascular diseases will be prospectively enrolled. Peripheral blood samples will be analyzed using untargeted lipidomic profiling in one cohort and targeted ceramide assays in another cohort.
Age range
18 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Peripheral Serum Concentration of Cer(d18:1/18:1), nmol/L
Timeframe: Baseline
Peripheral Serum Concentration of Cer(d18:1/16:0), nmol/L
Timeframe: baseline
Peripheral Serum Concentration of Cer(d18:1/18:0), nmol/L
Timeframe: Baseline
Peripheral Serum Concentration of Cer(d18:1/20:0), nmol/L
Timeframe: Baseline
Peripheral Serum Concentration of Cer(d18:1/22:0), nmol/L
Timeframe: Baseline
Peripheral Serum Concentration of Cer(d18:1/24:0), nmol/L
Timeframe: Baseline
Peripheral Serum Concentration of Cer(d18:1/24:1), nmol/L
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/18:1), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/16:0), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/18:0), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/20:0), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/22:0), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/24:0), AU
Timeframe: Baseline
Normalized Relative Abundance of Serum Cer(d18:1/24:1), AU
Timeframe: Baseline