Cancer-related cognitive impairment (CRCI) affects a large proportion of non-central nervous system cancer survivors and can negatively impact cognitive functioning and daily life. Cognitive rehabilitation has shown promising results in addressing these difficulties. The goal of this pilot randomized controlled trial is to evaluate the feasibility, acceptability, and preliminary efficacy of the CanCOG®- Cognitive Rehabilitation in Cancer program in Portuguese adult cancer survivors with CRCI. Adult non-central nervous system cancer survivors (n=60) will be randomly assigned to receive either the CanCOG® intervention or treatment as usual. CanCOG® is a structured cognitive rehabilitation program designed to help cancer survivors manage cognitive difficulties through cognitive training exercises, psychoeducation, and compensatory strategy training. The program consists of six weekly sessions of 1 hour and 30 minutes each, delivered over six consecutive weeks. Sessions are administered in person in small groups (3-9 participants) and are led by a trained professional. The main focus of the study is to assess feasibility outcomes, including recruitment, retention, adherence to the intervention, and completion of study assessments, as well as acceptability and participant satisfaction. The study will also explore preliminary effects of the intervention on cognitive functioning (both perceived and objective), symptoms of anxiety and depression, and quality of life. Participants will complete assessments at baseline (2 weeks after the intervention), 2 weeks after the intervention, and at 3- and 6-month follow-ups. Some participants (10-15) will also take part in interviews to provide feedback on their experience with the program.
Age range
18 Years – 65 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Feasibility - Screening rate
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups.
Feasibility - Eligibility rate
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups
Feasibility - Consent rate
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups.
Feasibility - Retention rate
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups
Feasibility - Assesment completion rate
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups
Feasibility - Intervention adherence
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups
Feasibility - Intervention fidelity
Timeframe: Baseline (2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-ups
Acceptability - Participant retention and intervention adherence
Timeframe: Baseline ( 2 weeks before intervention), post-intervention (2 weeks after), and 3-month and 6-month follow-up.
Acceptability - Qualitative feedback
Timeframe: Post-intervention (2 weeks after)
Acceptability - ACRIS-CS
Timeframe: Baseline (2 weeks before intervention) and post-intervention (2 weeks after).