Association Between Central Sensitization and the Root Mean Square of Successive Differences (NCT07755332) | Clinical Trial Compass
CompletedNot Applicable
Association Between Central Sensitization and the Root Mean Square of Successive Differences
Turkey (Türkiye)45 participantsStarted 2026-01-01
Plain-language summary
The aim of this study was to examine the relationship between central sensitization and resting RMSSD (Root Mean Square of Successive Differences) in individuals exhibiting prolonged sitting behavior, controlling for potential confounding factors such as age, gender, and body mass index; and to evaluate whether participants, grouped according to sitting durations, differed in terms of RMSSD, central sensitization, balance, and executive cognitive function.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age range: Between 18 and 45 years of age.
* Sitting time: Having at least 30 hours of sitting time per week.
* Voluntary participation: Voluntarily agreeing to participate in the study.
* Cognitive and sensory capacity: Having the cognitive, auditory, and visual capacity to understand the study procedures and perform the tasks.
* Physical fitness: Not having any physical condition that would prevent the use of the HRV measuring device.
Exclusion Criteria:
* Having any cardiovascular, neurological, or systemic disease that interferes with physical activity,
* Using medications that may affect the autonomic nervous system within the last month,
* Having a history of cognitive impairment,
* Having engaged in strenuous exercise or had a febrile illness within the last 24 hours,
* Having a clinically diagnosed central sensitization syndrome,
* Being pregnant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.