CompletedPhase 4

Postoperative Pain After Dexamethasone Injection by Two Techniques in Irreversible Pulpitis

Egypt66 participantsStarted 2024-03-26

Plain-language summary

The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups: * Group I: buccinator injection of dexamethasone. * Group II: buccal infiltration of dexamethasone. * Group III (Control): IANB using local anesthesia only post operative pain will be evaluated subjectively by patients by VAS score after procedure immediately and follow up for 12, 24 and 72 hours and frequency of analgesic intake

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1- Both genders 2- Older than age of (18 to 60) years 3- Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study 4- Having a mandibular molar tooth with vital pulp 5- These patients were also suffering from symptomatic irreversible pulpitis ,intermittent or continuous sharp pain that lasts longer after removal of the stimulus 6- Patients with moderate to severe symptoms VAS≥4 Exclusion Criteria: * 1- Vulnerable group; pregnant females, mentally ill and diseased patientsetc.… 2- Patients irritable to local anesthesia 3- Patients who are supposed to take plain anesthesia 4- Use of analgesic or antibiotic within 6 hours before the visit 5- Absence of bleeding in the pulp chamber during cavity preparation 6- Severe periodontal disease b- Patients' randomization, allocation and blinding:

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

visual analogue score (VAS) from 0 to 10

Timeframe: postoperative 72 hours

Trial details

NCT IDNCT07755306

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-26

View on ClinicalTrials.gov More Post Operative Pain, Acute trials