An In-vivo Survival Rate of Different Onlay Materials Placed Over Endodontically Treated Molar Teeth (NCT07753941) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
An In-vivo Survival Rate of Different Onlay Materials Placed Over Endodontically Treated Molar Teeth
Jordan39 participantsStarted 2025-09-01
Plain-language summary
This study aims to evaluate the survival rates of onlays placed over posterior endodontically treated teeth restored with zirconia, lithium disilicate and lithium disilicate reinforced with zirconia. Additionally, it seeks to identify and assess the failure modes associated with these types of restorations.
Who can participate
Age range
17 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients must have good general health.
. Patients must be 17 to 60 years old.
. Exclusively permanent molar teeth (first or second molars) needing restoration after endodontic therapy.
. The tooth needs adequate residual structure to support an Onlay repair, with minimum of 50% of the coronal structure maintained.
. Absence of Active Caries: The tooth and surrounding teeth ought to be free of illnesses or other agents compromising the restoration.
. Endodontic Status: Radiographic evidence of adequate obturation and the lack of periapical pathology justify the excellent root canal treatment the tooth underwent.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number and Proportion of Successful Onlay Restorations in Posterior Endodontically Treated Teeth Assessed by the Modified United States Public Health Service (USPHS) Criteria
Timeframe: 6 months and 12 months post-cementation
. The tooth and surrounding tissues must show periodontal stability free of evidence of active periodontal disease (probing depth \< 4 mm, lack of movement, and no bleeding following probing).
. The tooth must be in functional occlusion or have a specified occlusal contact with the opposite dentition.
Exclusion criteria
. The tooth had past treatment with a crown or onlay.
. Patients have any known allergies to the components utilized in the Onlay restoration-that is, composite resin, ceramic, or adhesive compounds.