A Clinical Trial Examining the Efficacy of a Novel Acne Treatment Serum (NCT07752368) | Clinical Trial Compass
CompletedNot Applicable
A Clinical Trial Examining the Efficacy of a Novel Acne Treatment Serum
United States25 participantsStarted 2023-06-01
Plain-language summary
This single-group, open-label clinical trial examines the efficacy of Cool as a Cucumber's Acne Treatment Serum in adults with acne-prone skin. The study will enroll 25 male and female participants between the ages of 24 and 47 who will use the serum for eight weeks, with assessments conducted virtually at Baseline, Week 4, and Week 8.
The primary objective is to evaluate the effects of the Acne Treatment Serum on facial acne using the Validated Acne Quality-of-Life Scale (Acne QoL) and expert-graded before-and-after photographs. Secondary objectives include evaluating changes in skin texture, uneven skin tone, hyperpigmentation, redness, sebum production, and fine lines and wrinkles via self-reported questionnaires.
Who can participate
Age range
24 Years – 47 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female between the ages of 24-47 (between 2-4 males, the remainder females)
* Actively has acne (non-inflamed and/or inflamed acne)
* Has previously used or is currently using exfoliating acids (AHAs / BHA) and is willing to stop this for the duration of the study
* Has not experienced sunburn on the face in the last month
* No open wounds, sores, or non-acne related lesions on the face
* Generally healthy - don't live with any uncontrolled chronic disease
* Willing to apply SPF on a daily basis during the study and to use other sun protection on the face (i.e. a hat)
* Must be willing to avoid products with coconut oil and shea butter, and Ethylhexyl Palmitate for the duration of the study
* Must be willing to cut out whey protein and cow's milk from their diet for the duration of the study
* Must be willing to avoid biotin products or supplements for the duration of the study
* Must agree to avoid sun tanning, tanning beds, and self-tanning products for the duration of the study
Exclusion Criteria:
* Any pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
* Anyone with known severe allergic reactions
* Women who are pregnant, breastfeeding or attempting to become pregnant
* Unwilling to follow the study protocol
* Smoker
* Anyone consuming products containing Tetrahydrocannabinol (THC)
* Identifies as a person with sensitive skin
* Anyone currently on …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.