Mental Rotation and Motor Imagery Training in Multiple Sclerosis (NCT07749690) | Clinical Trial Compass
CompletedNot Applicable
Mental Rotation and Motor Imagery Training in Multiple Sclerosis
Turkey (Türkiye)54 participantsStarted 2024-02-15
Plain-language summary
This randomized controlled trial investigated the effects of sequential laterality, motor imagery, and mental rotation training in individuals with relapsing-remitting multiple sclerosis. Both groups received conventional physiotherapy, while the intervention group received structured cognitive-motor training and the control group received active visual-attention training.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosed with definite relapsing-remitting multiple sclerosis by a neurologist according to the revised McDonald criteria
* Not experiencing an acute MS relapse
* Mini Mental State Examination score ≥24
* No clinical MS relapse within the previous 3 months
* No corticosteroid treatment for an MS relapse within the previous 3 months
* Expanded Disability Status Scale score between 1.5 and 6.0
* Modified Ashworth Scale score ≤2
* Sufficient communication ability to understand visual and verbal instructions and follow the training protocol
* Able to attend at least 80% of the planned sessions
* Able to complete the Movement Imagery Questionnaire-3
Exclusion Criteria:
* Any medication change within the previous 3 months
* Uncorrected severe visual or hearing impairment
* A communication disorder preventing the perception of or response to the visual and verbal stimuli used in the study
* Participation in another structured upper-extremity rehabilitation program or interventional study during the study period
* Presence of an additional neurological disorder
* Advanced sensory loss or proprioceptive impairment that could affect participation in the intervention
* Botulinum toxin injection within the previous 3 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The Purdue Spatial Visualization Test
Timeframe: Baseline and immediately after the 6-week intervention.