Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Ou… (NCT07748767) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Outcomes
184 participantsStarted 2027-01-01
Plain-language summary
With strict quality control procedures applied throughout microplastic testing, this study will assess the association between baseline circulating micro-nanoplastic exposure and coronary microvascular dysfunction, as well as subsequent long-term cardiovascular outcomes.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects with clinical indications for invasive coronary angiography and coronary functional assessment;
* Voluntarily sign the written informed consent form.
Exclusion Criteria:
* History of previous myocardial infarction;
* History of prior PCI or coronary artery bypass grafting (CABG);
* Intraoperative coronary angiography shows non-left main coronary artery diameter stenosis \>90%, or left main coronary artery diameter stenosis \>50%;
* Left ventricular ejection fraction \< 35%;
* Severe valvular heart disease with planned or prior valve replacement, confirmed cardiomyopathy, or constrictive pericarditis;
* Active inflammatory disease;
* Active malignant tumor or life expectancy \< 1 year;
* Pregnant or lactating women;
* Subjects who refuse to comply with the pollution control measures set in this study;
* Currently participating in other interventional clinical trials.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.