Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Car… (NCT07748468) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
Singapore83 participantsStarted 2026-08-15
Plain-language summary
This study aims to evaluate the effects of antioxidant-rich supplementation on skin carotenoid status, antioxidant status, and cardiometabolic health in overweight and obese individuals. The study may provide additional scientific evidence to support the further refinement of current dietary and nutritional recommendations.
Who can participate
Age range
21 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Able to give informed consent (AMT score ≥ 8 for older adults \[65-70 years old\])
* Adults 21-70 years old
* English-literate
* Have venous access sufficient to allow for blood sampling as per the protocol
* No drastic change of diet for the past 1 year
* If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 3 years prior to starting the study
Exclusion Criteria:
* Weight change \> 3kg in the past 3 months
* Exercising vigorously over the past 3 months
* Taking medications or dietary supplements which may impact eye/skin health
* Taking lipid-lowering and blood pressure controlling medications less than 3 years
* Smoking
* Drinking more than 2 alcoholic drinks per day
* Pregnant, lactating, or planning pregnancy in the next 6 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Skin Carotenoid Score Measured by Prysm iO™ from Baseline to Week 12
Timeframe: Week 0, 4, 8, 12
2
Mean Change from Baseline in Blood Carotenoid Concentration