Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery (NCT07748247) | Clinical Trial Compass
Not Yet RecruitingPhase 4
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
Chile82 participantsStarted 2026-08-03
Plain-language summary
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years or older.
* Scheduled for elective laparoscopic gastric bypass surgery.
* Body mass index between 30 and 50 kg/m².
* American Society of Anesthesiologists physical status II or III.
* Able and willing to provide written informed consent.
Exclusion Criteria:
* Surgical procedure lasting less than 2 hours.
* Body mass index greater than 50 kg/m².
* Significant cardiac disease.
* Moderate or severe obstructive respiratory disease, including uncontrolled asthma or chronic obstructive pulmonary disease.
* Pregnancy or breastfeeding.
* Known allergy or contraindication to medications used during the intraoperative period.
* Personal or family history of malignant hyperthermia.
* Active illicit drug use or substance dependence.
* Advanced chronic kidney disease, defined as an estimated glomerular filtration rate below 60 mL/min.
* Myasthenia gravis or another neuromuscular junction disorder.
* Severe cognitive or psychiatric disorder.
* Refusal to participate or withdrawal of informed consent at any time.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.