Improving Management of Recipients of Care With HIV Viremia to Optimize Viral Suppression in Zamb… (NCT07747987) | Clinical Trial Compass
CompletedNot Applicable
Improving Management of Recipients of Care With HIV Viremia to Optimize Viral Suppression in Zambia: A Process and Outcome Evaluation
Zambia548 participantsStarted 2023-04-01
Plain-language summary
The Centre for Infectious Disease Research in Zambia (CIDRZ) as an implementing partner (IP) through its Centers for Disease Control and Prevention (CDC) and President's Emergency Plan for AIDS Relief (PEPFAR)-funded programs provides technical assistance to the Zambian Ministry of Health (MOH) to support the 95-95-95 HIV care cascade targets. Following the expansion of the DSD approach to cover non-established PLHIV, the MOH, with assistance from CIDRZ piloted the introduction of viremic clinics (VCs) as a DSD model in Lusaka to manage recipients of care (ROCs) with unsuppressed viral loads. In this paper, we describe and report on the programmatic performance and outcomes of VL testing at 6 and 12-months in PLHIV on first line ART in the VC model programme in Lusaka province as well as identify the patient and healthcare workers facilitators and barriers to improve viral suppression within the VCs.
Who can participate
Age range
15 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* RoCs will be included if they are aged 15 years and above ,
* Started first line ART before March 2020
* on ART at least 6 months of continuous ART treatment
* With complete medical records in smart care, HVL registers and enrolled with HVL RoCs and active
Inclusion criteria for IDIs:
* RoCs in the qualitative evaluation clinics
* Aged \>15 years old
* having received EAC in the past 6 months.
Inclusion criteria for FGDs :
\- Health care workers involved in the care of those who are not virally suppressed (treatment supporters, EAC counselors, professional healthcare workers)
Exclusion Criteria:
\- ROCs\< 15 years,
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial in Zambia focused on improving management for people with HIV who have detectable viral loads — if I'm struggling with viral suppression myself, what does the evidence from this completed study suggest about approaches that might help me?
2The trial was categorized as Phase NA, which often means it was evaluating a care process or program rather than a new drug — can you explain what kind of intervention was actually tested here, and whether anything like it is available in my current care setting?
3Since this study is already completed, have the results been published or shared yet, and if so, what did they find about which strategies were most effective at achieving viral suppression?
4The trial took place in Zambia, so the healthcare context may be very different from where I'm being treated — are the management approaches studied here relevant or transferable to my situation, or are there local programs with similar goals I should know about?
5If my current treatment isn't keeping my viral load undetectable, what options does my care team have right now, and how do they compare to whatever was being tested in this study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Viral suppression
Timeframe: 3 to 6 months
Trial details
NCT IDNCT07747987
SponsorCentre for Infectious Disease Research in Zambia