Assessment of Retinal Microvascular Changes by OCT Angiography in Diabetic Retinopathy (NCT07747428) | Clinical Trial Compass
RecruitingNot Applicable
Assessment of Retinal Microvascular Changes by OCT Angiography in Diabetic Retinopathy
Egypt100 participantsStarted 2026-01-01
Plain-language summary
This observational cross-sectional study aims to assess retinal microvascular changes using optical coherence tomography angiography (OCTA) in patients with diabetic retinopathy. The study will evaluate retinal vessel density and foveal avascular zone parameters and investigate their correlation with best-corrected visual acuity and glycemic control (HbA1c) across different stages of diabetic retinopathy. The findings may improve understanding of retinal microvascular alterations and their clinical significance.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
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Inclusion Criteria:
* Adults aged 18 to 80 years.
* Patients diagnosed with diabetic retinopathy.
* Ability to undergo complete ophthalmic examination including OCT and OCT angiography.
* Availability of HbA1c measurement within the study period.
* Ability and willingness to provide written informed consent.
Exclusion Criteria:
* Previous vitreoretinal surgery.
* Significant media opacity affecting image quality (e.g., dense cataract or vitreous hemorrhage).
* Other retinal vascular diseases (e.g., retinal vein occlusion).
* Glaucoma or optic nerve diseases affecting visual function.
* High myopia (\>6 diopters).
* Poor-quality OCTA images due to motion artifacts or poor fixation.
* Refusal or inability to provide informed consent.
Exclusion Criteria:
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Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Retinal Microvascular Changes Measured by OCT Angiography