Effect of PNF + Core Strengthening Exercise in Sub-acute Guillain Barre Syndrome (NCT07745556) | Clinical Trial Compass
CompletedNot Applicable
Effect of PNF + Core Strengthening Exercise in Sub-acute Guillain Barre Syndrome
Pakistan32 participantsStarted 2026-02-15
Plain-language summary
This randomized controlled trial will evaluate the effectiveness of proprioceptive neuromuscular facilitation combined with core strengthening exercises in Guillain barre syndrome patients on balance, strength and ADLS. A total of 32 participants will be recruited using purposive sampling and randomly assigned into two groups through the sealed envelope method. Balance will be assessed using berg balance scale, strength will be measured by MMT and ADLS will measure by berthal index at baseline and after completion of the intervention participants in the experimental group will receive PNF + core strengthening exercise four times in week for eight weeks, and conventional physical therapy will perform on control group .
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* participants diagnosed with Guillain Barré Syndrome (GBS) based on neurological criteria
* At the subacute or recovery stage of GBS, meaning within two to 12 weeks from disease onset
* Age ranges from 18 to 45 years
* Gender does not matter; both males and females can participate
* Medical stability of the patient and being medically cleared to engage in intensive rehabilitation by a physical Ability to give informed consent
Exclusion Criteria:
* Patients with cognitive disabilities and those who cannot follow commands
* Patients with unstable heart and breathing rates and other systemic disease
* Patients refusing to give their informed consent
* Presence of musculoskeletal problems with balance problems (recent fractures, arthritis)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.