Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders (NCT07744490) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders
China200 participantsStarted 2026-07-25
Plain-language summary
This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and obsessive-compulsive disorder, based on family history or subthreshold emotional or behavioral symptoms. Participants will be followed for two years. Clinical assessments, questionnaires, EEG, biological samples, and MRI will be collected at scheduled intervals. The study aims to identify factors associated with the onset and progression of these disorders and support early risk identification.
Who can participate
Age range
7 Years – 17 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Aged 7-17 years at enrollment.
. Meeting at least one of the following conditions: Having at least one first-degree relative with a depressive disorder, anxiety disorder, or obsessive-compulsive disorder; or exhibiting clinically relevant but subthreshold depressive, anxiety, obsessive-compulsive, or repetitive behavioral symptoms.
. Not meeting the full diagnostic criteria for a depressive disorder, anxiety disorder, or obsessive-compulsive disorder at baseline, as assessed using the K-SADS-PL.
. Willing and able to participate in the scheduled assessments and follow-up visits.
. Written informed consent provided by a parent or legal guardian and assent provided by the participant
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is focused on children and adolescents who are considered 'high risk' for developing depression, anxiety, or OCD — can you help me understand whether my child would fall into that high-risk category based on their current situation?
2Since this trial is described as 'not yet recruiting,' how soon is it expected to open, and is it worth waiting for, or should we be pursuing other evaluations or support for my child right now?
3This study seems to be about tracking and identifying mental health conditions early rather than treating them — does that mean my child wouldn't receive any active treatment through this trial, and if so, how would their mental health be monitored and supported if symptoms worsen during the study?
4Because this is a Phase NA observational-style study measuring how often depression, anxiety, or OCD develops over time, what would my child actually be asked to do as a participant — how many visits, assessments, or check-ins would be involved, and over what period?
5If my child participates in this tracking study and is later found to have developed one of these conditions, would they have access to treatment through the study, or would we need to seek care separately at that point?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Cumulative Incidence of Depressive Disorders, Anxiety Disorders, or Obsessive-Compulsive Disorder