The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Re… (NCT07744282) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Retrospective Multicenter Observational Study
8,000 participantsStarted 2026-08-15
Plain-language summary
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of preoperative depression on the incidence of postoperative delirium among elderly Chinese patients undergoing non-cardiac major surgery.
Who can participate
Age range
65 Years – 100 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 1\. Age ≥ 65 years, both genders 2. Elective non-cardiac major surgery 3. Completed preoperative depression assessment (PHQ-9) 4. Completed postoperative delirium assessment (3D-CAM)
Exclusion Criteria:
* 1\. History of neurological or psychiatric disorders or use of neuropsychiatric medications 2. Impaired cognitive function or inability to complete preoperative follow-up 3. Transferred to ICU postoperatively 4. Missing delirium outcome data
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is looking at how depression before surgery might affect the chances of developing delirium after surgery in elderly patients — given my (or my family member's) situation, is preoperative depression something that should be assessed and documented before any planned procedure?
2Since this is a retrospective observational study that hasn't started recruiting yet, it won't be testing any new treatment — so how would participating in this kind of data-collection study actually benefit my care, if at all?
3The study focuses specifically on elderly Chinese patients, so is this research likely to be directly relevant to my own background and circumstances, and how does that affect whether the findings might apply to me?
4Postoperative delirium is a serious concern for older surgical patients — regardless of this study, what steps can we take now to screen for and reduce my risk of delirium after surgery?
5If preoperative depression does turn out to be a significant risk factor for postoperative delirium, as this study is investigating, should I be discussing depression screening or treatment as a standard part of my surgical preparation with my care team?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.