Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South Africa (NCT07741474) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South Africa
South Africa60 participantsStarted 2026-08
Plain-language summary
The Community Popular Opinion Leader (CPOL) is an intervention dveloped in the United States which identifies, trains, and enlists key opinion leaders within communities to deliver messages to peers and help link them to services. This project involves testing the feasibility and acceptability of such a localized version of the CPOL intervention in rural South Africa. This will be achieved through a pilot intervention in three purposively selected communities in the Hlabisa sub-district of uMkhanyakude district, KwaZulu-Natal. The investigators will select potential peer leaders in three ways (at random; based on nominations by peers; based on statistical analysis of previously collected social network data). Peer leaders will be invited to attend four weekly training sessions to learn about HIV prevention and persuasive communication. They will then be coached to start HIV prevention conversations with peers, including provision of HIV self-test kits and linkage to healthcare services. The investigators will evaluate this pilot using group discussions, in-depth interviews and brief pre/post questionnaires with session facilitators, peer leaders, contacted peers and healthcare providers. The investigators will analyse the data collected with the Practical, Robust Implementation and Sustainability Model (PRISM) dissemination and implementation framework, identifying factors likely to affect Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM).
Who can participate
Age range
18 Years – 28 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Resident in Sixhumene study area household
Exclusion Criteria:
* Unable to provide informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on distributing HIV self-tests in rural South Africa using community opinion leaders — since it hasn't started recruiting yet, how realistic is it that I or someone I know could eventually participate, and what would that actually involve day-to-day?
2The trial's main goal is measuring how many HIV self-tests get handed out, rather than tracking individual health outcomes like treatment success — what does that mean for what I'd personally gain or learn by being involved?
3Since this is listed as Phase NA, which often means it's a community-level public health or behavioral study rather than a drug or device trial, can you help me understand whether this is even the right type of study for my specific situation?
4This study is set in rural South Africa — if I'm not located there or connected to that community, is there any way this trial would be relevant to my care, or are there similar HIV prevention programs closer to home that my doctor could point me toward?
5Given that this trial focuses on HIV self-testing distribution rather than treatment, if I'm already concerned about HIV exposure or have been recently diagnosed, would you recommend I pursue established testing and treatment options now rather than waiting to see if this study opens up?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of HIV self-tests distributed
Timeframe: From enrollment to 4 weeks after last training session