Investigating a Mediation Model of Emotion Regulation and Psychological Resilience in Relationshi… (NCT07741422) | Clinical Trial Compass
CompletedNot Applicable
Investigating a Mediation Model of Emotion Regulation and Psychological Resilience in Relationship Between Mindfulness and Negative Emotions Among College Students in Guangzhou
China135 participantsStarted 2026-04-01
Plain-language summary
This study examines whether a four-week mindfulness-based intervention can reduce depression, anxiety, and stress among college students in Guangzhou, China. It also investigates whether changes in mindfulness, emotion regulation, and psychological resilience may help explain the effects of the intervention.
Eligible participants will be randomly assigned to either a mindfulness intervention group or a health education control group. The intervention group will receive weekly mindfulness-based training and complete brief daily mindfulness practice, while the control group will receive health education sessions. Participants will complete questionnaires assessing mindfulness, cognitive reappraisal, expressive suppression, psychological resilience, depression, anxiety, and stress before and after the intervention and at follow-up.
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* \- Full-time college students enrolled at a participating institution in Guangzhou, China.
* Aged 18 to 30 years.
* Able to read and understand Chinese.
* Willing to provide informed consent.
* Completed the initial questionnaire assessment.
* Reported at least mild symptoms of depression, anxiety, or stress on at least one subscale of the Depression Anxiety Stress Scales-21.
* Willing and able to participate in the four-week intervention and complete the required assessm
Exclusion Criteria:
* \- Currently receiving psychiatric or psychological treatment.
* Diagnosed with a severe mental disorder or other severe psychopathology that could interfere with participation.
* At acute risk of suicide or self-harm.
* Currently participating in another psychological or mental health intervention.
* Currently engaging in regular mindfulness meditation or enrolled in another mindfulness-based program.
* Pregnant.
* Having a physical or medical condition that prevents participation in the intervention activities.
* Unable to complete the intervention or study assessments.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Depression, Anxiety, and Stress Symptoms Assessed by the Depression Anxiety Stress Scales-21
Timeframe: Baseline and immediately after the 4-week intervention