Multicenter Study on the Use of Intraoperative OCT in the Diagnosis and Management of Lens Diseases (NCT07741370) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Multicenter Study on the Use of Intraoperative OCT in the Diagnosis and Management of Lens Diseases
China1,200 participantsStarted 2024-03-01
Plain-language summary
This multicenter retrospective study will collect clinical data to investigate the associations between preoperative and intraoperative anterior segment structural changes and postoperative surgical outcomes in patients with lens disorders, and to evaluate the clinical benefits of intraoperative optical coherence tomography (iOCT) in lens surgery, with the aim of improving the diagnosis and treatment of lens-related diseases.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 years or older.
* Presence of lens opacity or abnormal lens position.
* Visual impairment affecting activities of daily living.
* Met the indications for lens surgery.
* Underwent lens surgery.
Exclusion Criteria:
* Active intraocular inflammation.
* Uncontrolled systemic disease, use of medications that could significantly affect surgery, or other standard contraindications to lens surgery.
* Incomplete or unreliable key preoperative examination data, including ocular biometry.
* Inadequate image quality due to poor fixation or other causes, rendering the images unsuitable for analysis.
* Incomplete intraoperative OCT recordings, such as interrupted recording or severe image freezing, affecting data evaluation.
* Other psychological or physical conditions that might interfere with study participation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Concordance Rate Between Preoperative and Intraoperative Diagnoses
Timeframe: From completion of the preoperative examinations through the end of surgery; diagnostic concordance is assessed after surgery.
Trial details
NCT IDNCT07741370
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine