By InvitationNot Applicable

Neurophysiological Effects of Daily Centrum Use on Mood and Well-Being: A Cognalyzer EEG Analysis in Adults Between 40-60

Canada30 participantsStarted 2026-07-20

Plain-language summary

The goal of this clinical trial is to learn whether 12 weeks of use of Centrum® Silver Daily Multivitamin can improve mood, and overall well-being in older adults The main questions it aims to answer are: 1. Does daily use of the multivitamin over a 12 week period improve well-being indicators as measured using EEG-based and subjective mood tests? 2. Does perturbation in mood effects due to cognitive load after a battery of cognitive assessments improve after 12 weeks of multivitamin intake.

Who can participate

Age range

40 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * be between the ages of 40 to 60 * Answered affirmatively that they have consumed, or are interested in consuming the investigational product * Willingness to comply with all study requirements, complete questionnaires, records, and assessments associated with the study and to complete the facility visit * Has given voluntary, written, informed consent to participate in the study Exclusion Criteria: * does not currently consume a multivitamin or dietary supplement that includes more than two micronutrients * Women who are pregnant or breastfeeding * Any objections that preclude the application of the EEG headset * Allergy or sensitivity to any products required for the EEG measurement (e.g. conductive gel) * Subjects with forehead skin/scalp health issues. (eg dermatitis, head lice, etc) * History of a clinically significant adverse event associated with the consumption of a multivitamin product or any of its stated ingredients * History of dementia, schizophrenia or other psychotic disorder, inclusive of alcohol or drug abuse within the last 12 months, interest or participation in drug abuse treatment within the past 60 days, or familial history of psychosis * History of any clinically significant brain injury, based on self-report * The participant is currently experiencing a migraine * Significant cardiovascular event in the past 6 months * Major surgery in the past 3 months * Self-reported HIV-, Hepatitis B- and/or C-positive diagnosis * Impairment…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in EEG-Derived Relaxation Level (REL)

Timeframe: Comparison after 12 weeks of product use.

Change in EEG-Derived Mental Confusion Level (COL)

Timeframe: Comparison after 12 weeks of product use.

Trial details

NCT IDNCT07740135

SponsorZentrela Inc.

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2026-10-30

View on ClinicalTrials.gov More Well-being/Quality of Life trials