Suprainguinal Fascia Iliaca Block vs. Adductor Canal Block for Analgesia After Total Knee Arthrop… (NCT07739108) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Suprainguinal Fascia Iliaca Block vs. Adductor Canal Block for Analgesia After Total Knee Arthroplasty
60 participantsStarted 2026-08-12
Plain-language summary
This study evaluates the analgesic efficacy and motor-sparing properties of ultrasound-guided Suprainguinal Fascia Iliaca Block (S-FIB) compared with Adductor Canal Block (ACB) in patients undergoing primary total knee arthroplasty (TKA). The main hypothesis is that ACB better preserves quadriceps muscle strength, allowing earlier functional mobilization, while providing comparable (non-inferior) analgesia to S-FIB.
Who can participate
Age range
45 Years – 100 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA Physical Status I, II, or III
* Scheduled for elective unilateral primary total knee arthroplasty
* Able to understand and operate the PCA device
* Written informed consent provided
Exclusion Criteria:
* Pre-existing lower-extremity neurological deficit or motor weakness (e.g., severe diabetic neuropathy)
* Chronic opioid use (\>30 mg oral morphine equivalents/day for \>3 months)
* Infection at the block site or systemic sepsis
* Coagulopathy or bleeding diathesis
* Allergy to local anesthetics or study medications
* Revision TKA or bilateral knee procedures
* Cognitive impairment or inability to perform mobility/pain assessments
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing two different nerve block techniques — the suprainguinal fascia iliaca block and the adductor canal block — to manage pain after knee replacement; can you explain the difference between these two approaches and which one you currently use for your patients?
2Since this trial is listed as 'not yet recruiting,' it may not be available to me right now — is there a timeline for when it might open, and would waiting for it affect my treatment plan?
3The trial's main goal is measuring postoperative pain scores using a numerical rating scale, but I'd also want to know about side effects like muscle weakness or falls — how do these two nerve block types compare in terms of those risks based on what's already known?
4This trial is listed as Phase NA, which often applies to procedure-based studies rather than drug trials — does that mean the safety profile of both blocks is already reasonably well established, and what does that mean for my decision about participating?
5If I don't join this trial, what nerve block or pain management approach would you recommend after my knee replacement, and how does it compare to what's being studied here?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postoperative Pain Intensity (NRS)
Timeframe: Postoperative hours 24 hour
Trial details
NCT IDNCT07739108
SponsorBursa Yuksek Ihtisas Training and Research Hospital