CompletedNot Applicable

Evaluating Facial Skin Quality Changes Post-Lipofilling

France15 participantsStarted 2021-01-10

Plain-language summary

The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer. The main questions it aims to answer are: How does full-face lipofilling alter clinical signs of aging, such as wrinkles, sagging, and skin texture, over a 6-month period? Which baseline biological characteristics (e.g., cellular stemness, extracellular matrix remodeling, angiogenesis) within the donor fat graft predict these clinical skin quality outcomes? Participants will: Undergo a standard full-face autologous fat transfer (lipofilling) procedure. Attend follow-up evaluation visits at 1.5, 3, and 6 months post-procedure. Undergo non-invasive clinical and instrumental skin assessments (e.g., standardized photography, 3D topography, echography, and cutometry). Complete self-assessment questionnaires regarding perceived skin changes and overall satisfaction with the procedure.

Who can participate

Age range

30 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Female patient volunteers
. Over the age of 30
. Who had decided to have adipose tissue injections and declared eligible to this intervention
. Nonsmoker or less than 5 cigarettes per day
. Informed about the study objectives and procedures, and able to understand them
. Willing and able to fulfil the study requirements and schedule
. Able to give their written informed consent
. French subjects recruited must be affiliated to the French social security system.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Wrinkles and Fine Lines Severity

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Pigmentation and Color Uniformity

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Elasticity, Sagging, and Structural Aging Signs

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Texture and Surface Quality

Timeframe: Baseline up to 6 months post-procedure

Trial details

NCT IDNCT07737639

SponsorL'Oreal

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2023-11-10

View on ClinicalTrials.gov More Facial Aging trials

Plain-language summary

Who can participate

Age range

30 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Female patient volunteers
. Over the age of 30
. Who had decided to have adipose tissue injections and declared eligible to this intervention
. Nonsmoker or less than 5 cigarettes per day
. Informed about the study objectives and procedures, and able to understand them
. Willing and able to fulfil the study requirements and schedule
. Able to give their written informed consent
. French subjects recruited must be affiliated to the French social security system.

What they're measuring

Change in Wrinkles and Fine Lines Severity

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Pigmentation and Color Uniformity

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Elasticity, Sagging, and Structural Aging Signs

Timeframe: Baseline up to 6 months post-procedure

Change in Skin Texture and Surface Quality

Timeframe: Baseline up to 6 months post-procedure

Evaluating Facial Skin Quality Changes Post-Lipofilling

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

Evaluating Facial Skin Quality Changes Post-Lipofilling

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

Exclusion criteria