Effects of Respiratory Muscle Training on Tongue Corticomotor Excitability (NCT07737015) | Clinical Trial Compass
CompletedNot Applicable
Effects of Respiratory Muscle Training on Tongue Corticomotor Excitability
Denmark20 participantsStarted 2024-10-01
Plain-language summary
The tongue plays a central role in essential oral functions, including swallowing, speech, and upper airway control. Its coordinated interaction with the respiratory system is particularly relevant in clinical conditions such as obstructive sleep apnea and dysphagia. While respiratory muscle training is increasingly used in these contexts, its effects on the neural control of tongue function remain poorly understood.
This randomized cross-over pilot study aimed to investigate the acute effects of inspiratory (IMT) and expiratory (EMT) muscle training on tongue corticomotor excitability using transcranial magnetic stimulation. These results will provide novel insight into the neurophysiological mechanisms linking respiratory interventions and oral motor control.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 years of age or older
* good general health
* ability to read and understand the project information
Exclusion Criteria:
* medical, physical or psychological disorder
* metal implants in the head
* medications affecting the nervous system
* craniofacial abnormalities
* neuromuscular or inflammatory diseases
* history of epilepsy
* presence of pacemaker or implanted medical devices
* pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Motor-evoked potentials
Timeframe: Measured two times: immediately before the training session (baseline) and immediately after completion of the training session (approximately 45 minutes after baseline)