Tissue Adhesive vs Silk Sutures After Mandibular Third Molar Extraction (NCT07735598) | Clinical Trial Compass
CompletedNot Applicable
Tissue Adhesive vs Silk Sutures After Mandibular Third Molar Extraction
Italy47 participantsStarted 2026-01-10
Plain-language summary
Summary: This study compares two methods used to close the gum after the surgical removal of impacted lower wisdom teeth: a medical tissue adhesive and traditional silk sutures. Both closure techniques are evaluated for postoperative pain, bleeding, healing, and the local inflammatory response.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18 years or older.
* Healthy individuals (ASA I or II) with no history of uncontrolled systemic disease.
* Presence of bilateral partially or completely impacted mandibular third molars requiring surgical extraction.
* Comparable clinical and radiographic characteristics of both mandibular third molars.
* Ability and willingness to provide written informed consent.
* Willingness and ability to comply with the study protocol and attend all scheduled follow-up visits.
Exclusion Criteria:
* Age younger than 18 years.
* Absence of bilateral impacted mandibular third molars requiring surgical extraction.
* Pregnancy or breastfeeding.
* Current smoking.
* Uncontrolled systemic diseases or medical conditions affecting wound healing or bone metabolism.
* Oncological or hematological disorders.
* Inability or unwillingness to provide informed consent or comply with the study protocol and follow-up schedule.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.