Sarcopenia Screening in Advanced Coxarthrosis: The SARCO-COX Study (NCT07734129) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Sarcopenia Screening in Advanced Coxarthrosis: The SARCO-COX Study
Spain150 participantsStarted 2026-07-01
Plain-language summary
The SARCO-COX study evaluates whether screening for sarcopenia (loss of muscle strength and mass) in adults aged 65 years or older with advanced hip osteoarthritis, followed by a structured postoperative exercise program, improves recovery after total hip replacement surgery compared with standard care.
Participants will undergo assessments of muscle strength, muscle mass, physical function, pain, and quality of life before surgery and during follow-up. Blood samples and a small muscle biopsy obtained during the planned surgery will be analyzed to study biomarkers related to muscle health.
A total of 150 people are expected to participate in this study. Participants will be divided into three groups:
* Group 1: People with sarcopenia who will take part in an exercise programme following surgery.
* Group 2: People with sarcopenia who will receive the usual care and follow-up after their surgery.
* Group 3: people without sarcopenia who are undergoing surgery and will receive the usual care and follow-up.
The study aims to determine whether early identification and targeted rehabilitation of sarcopenia can improve functional outcomes and quality of life after hip replacement.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects age \>= 65 years of age
* Previous diagnosis of advanced hip osteoarthritis.
* Patients who are on the surgical waiting list for total joint replacement hip.
* Barthel Index \> 80 points.
* That they will undergo surgery at the Regional University Hospital of Malaga.
Exclusion Criteria:
* Patients who refuse to accept and sign the informed consent form surgical intervention.
* Patients who refuse to accept and sign the informed consent form participation in the study.
* Subjects diagnosed with immunodeficiency or undergoing immunosuppressive treatment.
* Subjects diagnosed with inflammatory or hematological disease.
* Subjects with coagulation disorders.
* Subjects with lung disease, heart disease or unstable high blood pressure.
* Subjects diagnosed with neurodegenerative disease that prevents them from performing physical exercise.
* Subjects with psychiatric pathology that prevents the performance of physical exercise and adherence to treatment.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.