RecruitingNot Applicable

Midpoint Transverse Process to Pleura (MTP) Block vs Erector Spinae Plane (ESP) Block for Acute Herpes Zoster (HZ) Pain

Egypt90 participantsStarted 2026-07-01

Plain-language summary

The aim of this study is to compare the analgesic efficacy and safety of ultrasound-guided midpoint transverse process block versus ultrasound-guided erector spinae plane block in patients suffering from thoracic herpes zoster pain.

Who can participate

Age range

21 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 21-60 years. * Both sexes. * American Society of Anesthesiologists (ASA) physical status I-II. * Acute thoracic herpes zoster within 30 days of rash onset. * Moderate to severe pain \[numeric rating scale (NRS)≥4\]. Exclusion Criteria: * Refusal to participate. * Coagulopathy or anticoagulant therapy. * Infection at puncture site. * Allergy to study drugs. * Severe psychiatric illness or inability to assess pain. * Previous thoracic surgery deformity. * Uncontrolled Diabetic patient. * Chronic diseases as renal, hepatic, malignancy. * Patients with chronic disease need analgesia. * Patients are coming for more than 3 months (after healing of rash).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incidence of post-herpatic neuralgia

Timeframe: After 12 weeks of block

Trial details

NCT IDNCT07732556

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06-01

Contact for this trial

Mohamed A Kazamel, MBBCH

00201205997183 mohamed198330_pg@med.tanta.edu.eg

View on ClinicalTrials.gov More Midpoint Transverse Process to Pleura Block trials

Who can participate

Age range

21 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.