Not Yet RecruitingNot Applicable

Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage

France860 participantsStarted 2026-10-01

Plain-language summary

The ASPIR study aims to evaluate the cost-utility of outpatient manual vacuum aspiration compared with operating room electric aspiration for the management of first-trimester miscarriage. It is hypothesized that manual aspiration will demonstrate equivalent clinical efficacy and patient quality of life while reducing healthcare costs.

Who can participate

Age range

18 Years – 44 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female, aged 18-44 years * Ultrasound-confirmed first-trimester miscarriage requiring surgical management * Gestational age between 5 and 12 weeks of amenorrhea * Incomplete spontaneous abortion or ongoing non-viable pregnancy * Patient able to provide oral informed consent Exclusion Criteria: * Complete expulsion of pregnancy (endometrial thickness \< 15 mm) * Choice of medical treatment with misoprostol * Elective termination of pregnancy * Unwanted pregnancy * Pregnancy of unknown location, molar pregnancy * Known uterine malformation * Prior surgical aspiration for the current pregnancy * Intrauterine device in place * Contraindicating medications (e.g. anticoagulants) * Protected adults (under guardianship) * Inability to complete study questionnaires * Lack of social security coverage * Haemorrhagic miscarriage

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incremental cost-utility ratio (ICUR)

Timeframe: 3 months

Trial details

NCT IDNCT07732231

SponsorNantes University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-01-01

Contact for this trial

Thibault Thubert, Pr

+33253482443 thibault.thubert@chu-nantes.fr

View on ClinicalTrials.gov More Miscarriage trials