NLR, ELR and SII Index as Biomarkers of Asthma Control (NCT07730047) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
NLR, ELR and SII Index as Biomarkers of Asthma Control
Egypt140 participantsStarted 2026-08-01
Plain-language summary
This is Case control study aims to study Neutrophil-to-Lymphocyte Ratio (NLR), Eosinophil-to-Lymphocyte Ratio (ELR), and Systemic Immune Inflammation (SII) Index as Biomarkers of Asthma Controlin adult patients with bronchial asthma.
This study will investigate the association between these inflammatory indices and the level of asthma control to assess their potential value as simple ,readily available and cost -effective biomarkers in clinical practice.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients aged \> 18 years.
* Confirmed diagnosis of bronchial asthma according to Global Initiative for Asthma (GINA) guidelines.
* Patients who provided informed consent to participate in the study.
Exclusion Criteria:
* Patients with chronic respiratory diseases other than asthma.
* Acute respiratory infection within the previous 4 weeks.
* Patients with hematological disorders, malignancies, autoimmune diseases, or systemic inflammatory conditions that might affect blood cell counts.
* Patients taking systemic steroids, experiencing acute asthma attack (because infection may affect neutrophil level).
* Pregnant women.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is looking at blood markers like the NLR, ELR, and SII index to predict how well asthma is controlled — can you explain what these markers measure and whether my own blood work has ever shown anything relevant about them?
2Since this study isn't recruiting yet, how soon might it open, and is it worth waiting to see if I qualify, or should we focus on other options for managing my asthma right now?
3The trial uses the Asthma Control Test score as its main measure — how do I currently score on that test, and what does that tell us about how well my asthma is actually being controlled?
4Because this is an observational study measuring biomarkers rather than testing a new treatment, what would I actually be asked to do if I joined, and would it involve any changes to my current asthma medications or care?
5If these blood markers turn out to be useful predictors of asthma control, how might that change the way my asthma is monitored or treated in the future, and is there any similar testing already available to me today?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.