This clinical trial tests the feasibility and acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment. Adolescents treated with radiation therapy for cancer often experience persistent cognitive deficits and reduced brain resilience or the ability to preserve cognitive and emotional functioning despite stressors. Musical instrument training has been shown to enhance memory, academic skills, and emotional well-being in youth. Although guitars are often the most preferred instrument, ukuleles offer greater accessibility due to their simplicity, affordability, and suitability for younger users. The STRUM intervention consists of virtual active music therapy ukulele lessons, which may be a feasible and acceptable way to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment.
Age range
12 Years – 17 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Percentage of eligible participants who consent to participate in this study (feasibility)
Timeframe: At time of enrollment
Proportion of STRUM sessions completed (feasibility)
Timeframe: Up to 10 weeks
Average weekly practice minutes
Timeframe: Up to 10 weeks
Percentage of participants who complete ≥ 90% of the measures at each timepoint (feasibility)
Timeframe: Baseline, week 6, week 12, week 20
Acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention
Timeframe: Approximately 2 weeks following end of intervention (week 12)
Participant perspective on meaningfulness of the STRUM intervention
Timeframe: Approximately 2 weeks following end of intervention (week 12)
Change in brain resilience
Timeframe: Baseline, week 6, week 12, week 20