ER-VISION-AI Study (NCT07727590) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
ER-VISION-AI Study
South Korea1,000 participantsStarted 2027-01-01
Plain-language summary
Prospective, multicenter, randomized, open-label, blinded-endpoint (PROBE-like) clinical trial evaluating whether physician-supervised Generative Pre-trained Transformer (GPT)-assisted multimodal diagnostic support improves diagnostic concordance in emergency department patients presenting with acute cardiopulmonary symptoms.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥18 years
* Presentation to a participating emergency department with acute cardiopulmonary symptoms, including chest pain, dyspnea, palpitations, syncope, dizziness, or fever accompanied by cardiopulmonary symptoms
* Performance of both a standard 12-lead electrocardiogram and chest radiography during the initial emergency department evaluation
* Availability of initial clinical assessment, vital signs, laboratory findings, and all mandatory clinical information required for the multimodal AI workflow
* Expected emergency department observation or hospital admission for at least 24 hours
* Ability and willingness to provide written informed consent
Exclusion Criteria:
* Inability or refusal to provide written informed consent
* Requirement for immediate life-saving intervention that precludes completion of the study workflow
* Death before completion of the initial emergency department diagnostic assessment
* Electrocardiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation
* Chest radiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation
* Cardiac pacing rhythm
* Missing mandatory clinical information required for the multimodal Artificial intelligence (AI) workflow
* Previous enrollment in the ER-VISION-AI trial
* Inability to establish a blinded adjudicated reference diagnosis
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diagnostic concordance between the final emergency department diagnosis and the blinded adjudicated reference diagnosis established at hospital discharge.
Timeframe: During the index hospitalization, up to hospital discharge (average 3 days)