Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke (NCT07725211) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
Turkey (Türkiye)45 participantsStarted 2026-08-15
Plain-language summary
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
Forty-five participants will be randomly assigned to one of three groups: (1) neurodevelopmental treatment (NDT) alone, (2) NDT combined with high-repetition task-oriented training, or (3) NDT combined with high-intensity gait training. All participants will receive treatment 3 days per week for 8 weeks (24 sessions in total). Walking capacity (6-Minute Walk Test) and functional mobility (Timed Up and Go Test, modified Dynamic Gait Index, 10-Meter Walk Test) will be assessed before and after the intervention by an assessor blinded to group allocation. The study hypothesizes that adding structured, intensity-based training approaches to conventional NDT will lead to greater improvements in walking capacity than NDT alone.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and/or radiological findings
* Time since stroke onset of at least 6 months (chronic phase)
* Age between 18 and 75 years
* Ability to walk at least 10 meters independently, with or without an assistive device
* Functional Ambulation Category (FAC) score of 3 or higher
* Sufficient cognitive ability to understand and follow instructions (Mini-Mental State Examination score ≥ 24)
* Willingness to participate and provision of written informed consent
Exclusion Criteria:
* Recurrent stroke or bilateral hemispheric involvement
* Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise
* Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score \> 3)
* Orthopedic, rheumatological, or other neurological conditions affecting gait
* Severe visual or vestibular impairment
* Severe aphasia or cognitive impairment preventing participation in training or assessments
* Participation in another structured rehabilitation or exercise program during the study period
* Botulinum toxin injection to the lower extremity within the last 6 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.