Evaluation of Demineralized Dentin Matrix With and Without Injectable Platelet Rich Fibrin as Gra… (NCT07725029) | Clinical Trial Compass
CompletedNot Applicable
Evaluation of Demineralized Dentin Matrix With and Without Injectable Platelet Rich Fibrin as Grafting Materials
Egypt32 participantsStarted 2025-06-01
Plain-language summary
Thirty two healthy patients will be selected from the outpatient clinic of the oral and maxillofacial surgery department, faculty of dentistry, Mansoura university, to be included in this study with non restorable teeth in the maxillary esthetic area. After atraumatic teeth extraction, immediate implant placement will be done and buccal jumping gap will be filled by demineralized dentin matrix in study group and control one by demineralized dentin matrix mixed with in injectable platelet rich fibrin.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient age ranged between 18-40 years old.
* Patients seeking to replace non-restorable tooth / teeth in maxillary esthetic zone (anterior \&premolars) by using immediate implant placement.
* Cooperative patients with high motivation and good oral hygiene.
* Intact socket wall after tooth extraction.
* Jumping gap more than 2mm.
* Favorable occlusion without presence of parafunctional habits, eg; bruxism and clenching.
* Sufficient inter-arch space to accommodate the future prothesis.
* Patients able to comply with the required recall visits.
Exclusion Criteria:
* Patients with known systemic diseases, which can affect normal bone formation or blood coagulation.
* Presence of signs of acute infection or pus formation.
* Pregnancy.
* Smoking.
* Patients on bisphosphonate drug.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.