The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by mouth as different formulations.
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Maximum observed drug concentration (Cmax)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Area under concentration-curve from time 0 to the last quantifiable concentration (AUClast)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Area under concentration-time curve from time 0 to infinity (AUCinf)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Time to reach maximum observed concentration (tmax)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Terminal elimination rate constant (λz)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Terminal elimination half-life (t1/2λz)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Apparent total body clearance (CL/F)
Timeframe: At pre-defined intervals from Day 1 to Day 15
AstraZeneca Clinical Study Information Center
Apparent volume of distribution based on the terminal phase (Vz/F)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Ratio of elecoglipron (test formulation) to elecoglipron (reference formulation) based on AUCinf (R AUCinf)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Ratio of elecoglipron (test formulation) to elecoglipron (reference formulation) based on AUClast (R AUClast)
Timeframe: At pre-defined intervals from Day 1 to Day 15
Ratio of elecoglipron (test formulation) to elecoglipron (reference formulation) based on Cmax (R Cmax)
Timeframe: At pre-defined intervals from Day 1 to Day 15