Journavx to Treat Pain After Thumb Basal Joint Arthroplasty (NCT07723352) | Clinical Trial Compass
By InvitationNot Applicable
Journavx to Treat Pain After Thumb Basal Joint Arthroplasty
United States100 participantsStarted 2026-07-21
Plain-language summary
The purpose of this study is to find out how well suzetrigine, a newly FDA-approved non-opioid pain medication, works to relieve pain after thumb basal joint replacement surgery. The researchers believe that suzetrigine may provide effective pain relief during recovery without the use of opioid medications.
Who can participate
Age range
40 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 40-80 years.
* Undergoing thumb basal joint arthroplasty (BJA)
* Able to provide informed consent.
* Willing to comply with the study procedures.
Exclusion Criteria:
* History of substance abuse or chronic opioid use.
* Known allergies to acetaminophen, oxycodone, or suzetrigine.
* Severe renal or hepatic dysfunction
* Estimated glomerular filtration rate less than 15 ml/min/1.73m\^2
* History of kidney transplant
* Child-Pugh Class C
* History of liver failure
* Active hepatitis that can adversely influence hepatic function
* Has had prior surgery on the study hand within the last 6 months
* Is currently pregnant, planning to be pregnant, or breastfeeding
* Use of strong or moderate CYP3A inhibitors or inducers, or medications known to interact with suzetrigine
* Currently using a prescription pain medication other study medications
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.