Telerehabilitation in Alzheimer's Disease (NCT07722169) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Telerehabilitation in Alzheimer's Disease
48 participantsStarted 2026-10
Plain-language summary
Telemedicine has developed rapidly during the COVID-19 pandemic and is now integrated into the clinical practice of many hospitals. Telemedicine offers many advantages, and even after the end of the pandemic, many patients still choose to undergo healthcare visits remotely. However, the rapid expansion of telemedicine may be associated with the risk of providing patients with unvalidated and uncontrolled telehealth solutions, potentially negatively impacting their health.
In this study, the researchers aim to investigate the effectiveness of remote cognitive training in patients with mild-to-moderate Alzheimer's disease (AD) using tablets equipped with virtual reality-based cognitive exercises. The investigators also aim to evaluate the impact of online supervision of cognitive training by a neuropsychologist and to compare the costs and burden of home-based versus hospital-based cognitive training in patients with AD. This project will define the optimal modalities for cognitive telerehabilitation to ensure validated protocols for the continuity of care in AD.
Who can participate
Age range
50 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria for patients with Alzheimer's disease (AD):
* Age between 50 and 90 years.
* Diagnosis of Alzheimer's disease according to established diagnostic criteria.
* Mini-Mental State Examination (MMSE) score between 18 and 24.
* Stable pharmacological treatment for at least 3 months before enrolment.
* Ability and willingness to provide written informed consent.
Inclusion criteria for caregivers:
* Age ≥18 years.
* Availability to assist the patient throughout the study.
* Ability and willingness to provide written informed consent.
Exclusion criteria for patients with Alzheimer's disease (AD):
* Refusal or inability to provide written informed consent.
* History of psychiatric disorders.
* Significant cerebrovascular disease.
* Severe visual or hearing impairment that could interfere with study procedures.
* Psychosis.
* Major depressive disorder.
* Alcohol or substance abuse.
* Use of psychotropic medications that may interfere with neuropsychological assessment or study treatment.
* Concurrent participation in another interventional pharmacological clinical trial.
* Any contraindication to undergoing EEG recording.
Exclusion criteria for caregivers:
* Refusal or inability to provide written informed consent.
* History of psychiatric disorders.
* Major depressive disorder.
* Alcohol or substance abuse.
* Use of psychotropic medications that may interfere with neuropsychological assessment.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as 'not yet recruiting' — do you know when it's expected to open, and is it worth waiting for, or should we focus on other options in the meantime?
2The trial is measuring cognitive changes using the Montreal Cognitive Assessment, or MoCA — can you explain what that test measures and whether it would capture the kinds of changes that matter most for my situation?
3Since this is a telerehabilitation study, what would the actual day-to-day commitment look like — things like internet access, device requirements, or caregiver involvement — and is that realistic given my home setup?
4This trial is listed as Phase NA, which usually means it's not a standard drug trial — can you help me understand what kind of intervention is being tested and what that means for what we already know about its safety and effectiveness?
5Are there currently available cognitive rehabilitation programs or therapies for Alzheimer's that I could access right now, and how would those compare to waiting for and potentially joining this telerehabilitation trial?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Montreal Cognitive Assessment (MoCA)
Timeframe: (1) before telerehabilitation, (2) at the end of the 3-month rehabilitation period, and (3) 3 months following the end of treatment.