Graft Type and Outcomes After ACL Reconstruction in Female Athletes (NCT07722104) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
Spain82 participantsStarted 2026-08-01
Plain-language summary
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes. Participants will be followed for two years after surgery to evaluate graft failure rates, return to sport, knee stability, and patient-reported outcomes.
Who can participate
Age range
16 Years – 35 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female patients aged 16 to 35 years with skeletal maturity
* Active athlete: minimum two training sessions per week during the six months prior to injury in pivoting sports
* Confirmed complete ACL rupture by MRI and clinical examination
* Primary ACL reconstruction (first ligament surgery on the index knee)
* Time from injury to surgery no longer than 6 months
* Signed informed consent
Exclusion Criteria:
* Previous ligament surgery on either knee
* Multiligament injury: simultaneous PCL, grade III MCL or LCL injury
* Neuromuscular, rheumatological or systemic pathology interfering with rehabilitation or functional assessments
* Pre-existing radiological osteoarthritis grade Kellgren-Lawrence ≥2 in the index knee
* Inability to complete 24-month follow-up protocol
* Pregnancy at inclusion or during follow-up period
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.