The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy (NCT07721623) | Clinical Trial Compass
Not Yet RecruitingEarly Phase 1
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
900 participantsStarted 2026-08-15
Plain-language summary
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods. The prevalence of uterine fibroids is significantly affecting up to 70-80% of women by the age of 50, with an inconsistent impact on women of African origin. Carbitocin is a synthetic analogue of oxytocin which has a longer half-life than oxytocin. A Cochrane review and meta-analysis studies found that carbitocin reduced the use of additional uterotonics and transfusion. However, few of these studies was done during myomectomy.
Who can participate
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* All consented women booked for myomectomy.
* No know allergy to Cabetocin.
* Billed for open abdominal myomectomy.
Exclusion Criteria:
* Declined consent
* Allergy to Cabetocin
* Planned for additional uterotonic
* Prior history of thromboembolism,
* With bleeding disorders
* History of renal disease
* History of liver pathology
* Chronic anaemia
* Billed for vaginal or laparoscopic myomectomy
* Patients received preoperative embolization or Gn-Rh analogue.
* Type 8: Non-myometrial or ectopic
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Haemoglobin Change
Timeframe: 24months
Trial details
NCT IDNCT07721623
SponsorAlex Ekwueme Federal University Teaching Hospital